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How much GPU memory does Mistral Medium 3.5 128B need?

Mistral Medium 3.5 128B by Mistral AI has 128B parameters. Its weights take 255 GB at 16-bit, 128 GB at 8-bit and 71.8 GB at 4-bit; released in FP8, its files are 134 GB. Each token of a conversation adds 360 KB of KV cache, so a 32K conversation holds 11.8 GB.

Mistral AI · released in FP8

Mistral Medium 3.5 128B at a glance

Parameters
128B
As released
134 GB
Its FP8 files
At 16-bit
255 GB
At 4-bit
71.8 GB
NVFP4
KV cache a token
360 KB
At 16-bit
Longest context
262,144
Tokens

GPUs needed at each number format

For 1 conversation of 32,768 tokens with a 16-bit KV cache, counting 92% of each GPU's memory as vLLM does. Under each count, the most tokens a second memory allows.

GPUMemory16-bit8-bit4-bit
L424 GB16 GPUs9 tokens/s8 GPUs17 tokens/s4 GPUs14 tokens/s
GeForce RTX 509032 GB16 GPUs54 tokens/s8 GPUs103 tokens/s4 GPUs86 tokens/s
L40S48 GB8 GPUs26 tokens/s4 GPUs25 tokens/s2 GPUs21 tokens/s
A100 80GB80 GB4 GPUs31 tokens/s2 GPUs29 tokens/s2 GPUs49 tokens/s
H10080 GB4 GPUs50 tokens/s2 GPUs48 tokens/s2 GPUs80 tokens/s
RTX PRO 6000 Blackwell96 GB4 GPUs27 tokens/s2 GPUs26 tokens/s1 GPU21 tokens/s
DGX Spark128 GB4 GPUs4.1 tokens/s2 GPUs3.9 tokens/s1 GPU3.3 tokens/s
H200141 GB4 GPUs72 tokens/s2 GPUs69 tokens/s1 GPU57 tokens/s
B200180 GB2 GPUs60 tokens/s1 GPU57 tokens/s1 GPU96 tokens/s
Instinct MI300X192 GB2 GPUs40 tokens/s1 GPU38 tokens/s1 GPU63 tokens/s
Instinct MI325X256 GB2 GPUs45 tokens/s1 GPU43 tokens/s1 GPU72 tokens/s
Instinct MI355X288 GB2 GPUs60 tokens/s1 GPU57 tokens/s1 GPU96 tokens/s

Questions

How much VRAM does Mistral Medium 3.5 128B need?
255 GB for its weights at 16-bit, 128 GB at 8-bit and 71.8 GB at 4-bit, plus the KV cache: 360 KB for each token, 11.8 GB for a conversation of 32K tokens and 94.5 GB at its longest context of 262,144 tokens. The server also keeps about 8% of each GPU free.
Can Mistral Medium 3.5 128B run on 1 GPU?
Yes, at 4-bit: the smallest single GPU here that holds it with a 32K conversation is the RTX PRO 6000 Blackwell.
How many H100s does Mistral Medium 3.5 128B need?
With 1 conversation of 32K tokens, 4 H100s at 16-bit and 2 H100s at 4-bit. Each H100 has 80 GB, of which vLLM uses 92% by default.
Can I run Mistral Medium 3.5 128B on an RTX 5090?
The RTX 5090 has 32 GB. With a 32K conversation, Mistral Medium 3.5 128B needs 4 GeForce RTX 5090s at 4-bit and 16 GeForce RTX 5090s (2 servers of 8) at 16-bit.
How fast does Mistral Medium 3.5 128B run?
At 4-bit on 2 H100s, memory lets 1 conversation get at most 80 tokens a second. Real servers reach part of that ceiling, and each conversation gets less when many run at once.